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Targeting TNF-α and NF-κB Activation by Bee Venom: Role in Suppressing Adjuvant Induced Arthritis and Methotrexate Hepatotoxicity in Rats
Low dose methotrexate is the cornerstone for the treatment of rheumatoid arthritis. One of its major drawbacks is hepatotoxicity, resulting in poor compliance of therapy. Dissatisfied arthritis patients are likely to seek the option of complementary and alternative medicine such as bee venom. The co...
Autores principales: | Darwish, Samar F., El-Bakly, Wesam M., Arafa, Hossam M., El-Demerdash, Ebtehal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835890/ https://www.ncbi.nlm.nih.gov/pubmed/24278124 http://dx.doi.org/10.1371/journal.pone.0079284 |
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