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The Pathogen- and Incidence-Based DALY Approach: An Appropriated Methodology for Estimating the Burden of Infectious Diseases

In 2009, the European Centre for Disease Prevention and Control initiated the ‘Burden of Communicable Diseases in Europe (BCoDE)’ project to generate evidence-based and comparable burden-of-disease estimates of infectious diseases in Europe. The burden-of-disease metric used was the Disability-Adjus...

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Autores principales: Mangen, Marie-Josée J., Plass, Dietrich, Havelaar, Arie H., Gibbons, Cheryl L., Cassini, Alessandro, Mühlberger, Nikolai, van Lier, Alies, Haagsma, Juanita A., Brooke, R. John, Lai, Taavi, de Waure, Chiara, Kramarz, Piotr, Kretzschmar, Mirjam E. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835936/
https://www.ncbi.nlm.nih.gov/pubmed/24278167
http://dx.doi.org/10.1371/journal.pone.0079740
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author Mangen, Marie-Josée J.
Plass, Dietrich
Havelaar, Arie H.
Gibbons, Cheryl L.
Cassini, Alessandro
Mühlberger, Nikolai
van Lier, Alies
Haagsma, Juanita A.
Brooke, R. John
Lai, Taavi
de Waure, Chiara
Kramarz, Piotr
Kretzschmar, Mirjam E. E.
author_facet Mangen, Marie-Josée J.
Plass, Dietrich
Havelaar, Arie H.
Gibbons, Cheryl L.
Cassini, Alessandro
Mühlberger, Nikolai
van Lier, Alies
Haagsma, Juanita A.
Brooke, R. John
Lai, Taavi
de Waure, Chiara
Kramarz, Piotr
Kretzschmar, Mirjam E. E.
author_sort Mangen, Marie-Josée J.
collection PubMed
description In 2009, the European Centre for Disease Prevention and Control initiated the ‘Burden of Communicable Diseases in Europe (BCoDE)’ project to generate evidence-based and comparable burden-of-disease estimates of infectious diseases in Europe. The burden-of-disease metric used was the Disability-Adjusted Life Year (DALY), composed of years of life lost due to premature death (YLL) and due to disability (YLD). To better represent infectious diseases, a pathogen-based approach was used linking incident cases to sequelae through outcome trees. Health outcomes were included if an evidence-based causal relationship between infection and outcome was established. Life expectancy and disability weights were taken from the Global Burden of Disease Study and alternative studies. Disease progression parameters were based on literature. Country-specific incidence was based on surveillance data corrected for underestimation. Non-typhoidal Salmonella spp. and Campylobacter spp. were used for illustration. Using the incidence- and pathogen-based DALY approach the total burden for Salmonella spp. and Campylobacter spp. was estimated at 730 DALYs and at 1,780 DALYs per year in the Netherlands (average of 2005–2007). Sequelae accounted for 56% and 82% of the total burden of Salmonella spp. and Campylobacter spp., respectively. The incidence- and pathogen-based DALY methodology allows in the case of infectious diseases a more comprehensive calculation of the disease burden as subsequent sequelae are fully taken into account. Not considering subsequent sequelae would strongly underestimate the burden of infectious diseases. Estimates can be used to support prioritisation and comparison of infectious diseases and other health conditions, both within a country and between countries.
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spelling pubmed-38359362013-11-25 The Pathogen- and Incidence-Based DALY Approach: An Appropriated Methodology for Estimating the Burden of Infectious Diseases Mangen, Marie-Josée J. Plass, Dietrich Havelaar, Arie H. Gibbons, Cheryl L. Cassini, Alessandro Mühlberger, Nikolai van Lier, Alies Haagsma, Juanita A. Brooke, R. John Lai, Taavi de Waure, Chiara Kramarz, Piotr Kretzschmar, Mirjam E. E. PLoS One Research Article In 2009, the European Centre for Disease Prevention and Control initiated the ‘Burden of Communicable Diseases in Europe (BCoDE)’ project to generate evidence-based and comparable burden-of-disease estimates of infectious diseases in Europe. The burden-of-disease metric used was the Disability-Adjusted Life Year (DALY), composed of years of life lost due to premature death (YLL) and due to disability (YLD). To better represent infectious diseases, a pathogen-based approach was used linking incident cases to sequelae through outcome trees. Health outcomes were included if an evidence-based causal relationship between infection and outcome was established. Life expectancy and disability weights were taken from the Global Burden of Disease Study and alternative studies. Disease progression parameters were based on literature. Country-specific incidence was based on surveillance data corrected for underestimation. Non-typhoidal Salmonella spp. and Campylobacter spp. were used for illustration. Using the incidence- and pathogen-based DALY approach the total burden for Salmonella spp. and Campylobacter spp. was estimated at 730 DALYs and at 1,780 DALYs per year in the Netherlands (average of 2005–2007). Sequelae accounted for 56% and 82% of the total burden of Salmonella spp. and Campylobacter spp., respectively. The incidence- and pathogen-based DALY methodology allows in the case of infectious diseases a more comprehensive calculation of the disease burden as subsequent sequelae are fully taken into account. Not considering subsequent sequelae would strongly underestimate the burden of infectious diseases. Estimates can be used to support prioritisation and comparison of infectious diseases and other health conditions, both within a country and between countries. Public Library of Science 2013-11-20 /pmc/articles/PMC3835936/ /pubmed/24278167 http://dx.doi.org/10.1371/journal.pone.0079740 Text en © 2013 Mangen et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Mangen, Marie-Josée J.
Plass, Dietrich
Havelaar, Arie H.
Gibbons, Cheryl L.
Cassini, Alessandro
Mühlberger, Nikolai
van Lier, Alies
Haagsma, Juanita A.
Brooke, R. John
Lai, Taavi
de Waure, Chiara
Kramarz, Piotr
Kretzschmar, Mirjam E. E.
The Pathogen- and Incidence-Based DALY Approach: An Appropriated Methodology for Estimating the Burden of Infectious Diseases
title The Pathogen- and Incidence-Based DALY Approach: An Appropriated Methodology for Estimating the Burden of Infectious Diseases
title_full The Pathogen- and Incidence-Based DALY Approach: An Appropriated Methodology for Estimating the Burden of Infectious Diseases
title_fullStr The Pathogen- and Incidence-Based DALY Approach: An Appropriated Methodology for Estimating the Burden of Infectious Diseases
title_full_unstemmed The Pathogen- and Incidence-Based DALY Approach: An Appropriated Methodology for Estimating the Burden of Infectious Diseases
title_short The Pathogen- and Incidence-Based DALY Approach: An Appropriated Methodology for Estimating the Burden of Infectious Diseases
title_sort pathogen- and incidence-based daly approach: an appropriated methodology for estimating the burden of infectious diseases
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835936/
https://www.ncbi.nlm.nih.gov/pubmed/24278167
http://dx.doi.org/10.1371/journal.pone.0079740
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