Cargando…
The Microprocessor controls the activity of mammalian retrotransposons
More than half of the human genome is made of Transposable Elements. Their ongoing mobilization is a driving force in genetic diversity; however, little is known about how the host regulates their activity. Here, we show that the Microprocessor (Drosha-DGCR8), which is required for microRNA biogenes...
Autores principales: | Heras, Sara R., Macias, Sara, Plass, Mireya, Fernandez, Noemí, Cano, David, Eyras, Eduardo, Garcia-Perez, José L., Cáceres, Javier F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836241/ https://www.ncbi.nlm.nih.gov/pubmed/23995758 http://dx.doi.org/10.1038/nsmb.2658 |
Ejemplares similares
-
DGCR8 HITS-CLIP reveals novel functions for the Microprocessor
por: Macias, Sara, et al.
Publicado: (2012) -
Control of mammalian retrotransposons by cellular RNA processing activities
por: Heras, Sara R, et al.
Publicado: (2014) -
Drosha Regulates Gene Expression Independently of RNA Cleavage Function
por: Gromak, Natalia, et al.
Publicado: (2013) -
Drosha Regulates Gene Expression Independently of RNA Cleavage Function
por: Gromak, Natalia, et al.
Publicado: (2014) -
Differentiated evolutionary rates in alternative exons and the implications for splicing regulation
por: Plass, Mireya, et al.
Publicado: (2006)