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The Microprocessor controls the activity of mammalian retrotransposons

More than half of the human genome is made of Transposable Elements. Their ongoing mobilization is a driving force in genetic diversity; however, little is known about how the host regulates their activity. Here, we show that the Microprocessor (Drosha-DGCR8), which is required for microRNA biogenes...

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Detalles Bibliográficos
Autores principales: Heras, Sara R., Macias, Sara, Plass, Mireya, Fernandez, Noemí, Cano, David, Eyras, Eduardo, Garcia-Perez, José L., Cáceres, Javier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836241/
https://www.ncbi.nlm.nih.gov/pubmed/23995758
http://dx.doi.org/10.1038/nsmb.2658

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