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Exploring the Composition of Protein-Ligand Binding Sites on a Large Scale

The residue composition of a ligand binding site determines the interactions available for diffusion-mediated ligand binding, and understanding general composition of these sites is of great importance if we are to gain insight into the functional diversity of the proteome. Many structure-based drug...

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Detalles Bibliográficos
Autores principales: Khazanov, Nickolay A., Carlson, Heather A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836696/
https://www.ncbi.nlm.nih.gov/pubmed/24277997
http://dx.doi.org/10.1371/journal.pcbi.1003321