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Multiscale Modeling of Influenza A Virus Infection Supports the Development of Direct-Acting Antivirals
Influenza A viruses are respiratory pathogens that cause seasonal epidemics with up to 500,000 deaths each year. Yet there are currently only two classes of antivirals licensed for treatment and drug-resistant strains are on the rise. A major challenge for the discovery of new anti-influenza agents...
Autores principales: | Heldt, Frank S., Frensing, Timo, Pflugmacher, Antje, Gröpler, Robin, Peschel, Britta, Reichl, Udo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836700/ https://www.ncbi.nlm.nih.gov/pubmed/24278009 http://dx.doi.org/10.1371/journal.pcbi.1003372 |
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