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Pathways-Driven Sparse Regression Identifies Pathways and Genes Associated with High-Density Lipoprotein Cholesterol in Two Asian Cohorts

Standard approaches to data analysis in genome-wide association studies (GWAS) ignore any potential functional relationships between gene variants. In contrast gene pathways analysis uses prior information on functional structure within the genome to identify pathways associated with a trait of inte...

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Detalles Bibliográficos
Autores principales:	Silver, Matt, Chen, Peng, Li, Ruoying, Cheng, Ching-Yu, Wong, Tien-Yin, Tai, E-Shyong, Teo, Yik-Ying, Montana, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836716/ https://www.ncbi.nlm.nih.gov/pubmed/24278029 http://dx.doi.org/10.1371/journal.pgen.1003939

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