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A Unique SUMO-2-Interacting Motif within LANA Is Essential for KSHV Latency

Kaposi's sarcoma-associated herpesvirus (KSHV) stabilizes hypoxia-inducible factor α (HIF-1α) during latent infection, and HIF-1α reactivates lytic replication under hypoxic stress. However, the mechanism utilized by KSHV to block lytic reactivation with the accumulation of HIF-1α in latency re...

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Detalles Bibliográficos
Autores principales:	Cai, Qiliang, Cai, Shen, Zhu, Caixia, Verma, Suhbash C., Choi, Ji-Young, Robertson, Erle S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836728/ https://www.ncbi.nlm.nih.gov/pubmed/24278015 http://dx.doi.org/10.1371/journal.ppat.1003750

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