Type I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia

Interferons (IFNs) are a group of cytokines with a well-established antiviral function. They can be induced by viral infection, are secreted and bind to specific receptors on the same or neighbouring cells to activate the expression of hundreds of IFN stimulated genes (ISGs) with antiviral function....

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Detalles Bibliográficos
Autores principales: Crotta, Stefania, Davidson, Sophia, Mahlakoiv, Tanel, Desmet, Christophe J., Buckwalter, Matthew R., Albert, Matthew L., Staeheli, Peter, Wack, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836735/
https://www.ncbi.nlm.nih.gov/pubmed/24278020
http://dx.doi.org/10.1371/journal.ppat.1003773

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