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Brd4 Is Displaced from HPV Replication Factories as They Expand and Amplify Viral DNA
Replication foci are generated by many viruses to concentrate and localize viral DNA synthesis to specific regions of the cell. Expression of the HPV16 E1 and E2 replication proteins in keratinocytes results in nuclear foci that recruit proteins associated with the host DNA damage response. We show...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836737/ https://www.ncbi.nlm.nih.gov/pubmed/24278023 http://dx.doi.org/10.1371/journal.ppat.1003777 |