Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

The major histocompatibility complex (MHC) region is strongly associated with multiple sclerosis (MS) susceptibility. HLA-DRB1*15:01 has the strongest effect, and several other alleles have been reported at different levels of validation. Using SNP data from genome-wide studies, we imputed and teste...

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Detalles Bibliográficos
Autores principales: Patsopoulos, Nikolaos A., Barcellos, Lisa F., Hintzen, Rogier Q., Schaefer, Catherine, van Duijn, Cornelia M., Noble, Janelle A., Raj, Towfique, Gourraud, Pierre-Antoine, Stranger, Barbara E., Oksenberg, Jorge, Olsson, Tomas, Taylor, Bruce V., Sawcer, Stephen, Hafler, David A., Carrington, Mary, De Jager, Philip L., de Bakker, Paul I. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836799/
https://www.ncbi.nlm.nih.gov/pubmed/24278027
http://dx.doi.org/10.1371/journal.pgen.1003926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836799/
https://www.ncbi.nlm.nih.gov/pubmed/24278027
http://dx.doi.org/10.1371/journal.pgen.1003926

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