Cargando…

Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

The major histocompatibility complex (MHC) region is strongly associated with multiple sclerosis (MS) susceptibility. HLA-DRB1*15:01 has the strongest effect, and several other alleles have been reported at different levels of validation. Using SNP data from genome-wide studies, we imputed and teste...

Descripción completa

Detalles Bibliográficos
Autores principales:	Patsopoulos, Nikolaos A., Barcellos, Lisa F., Hintzen, Rogier Q., Schaefer, Catherine, van Duijn, Cornelia M., Noble, Janelle A., Raj, Towfique, Gourraud, Pierre-Antoine, Stranger, Barbara E., Oksenberg, Jorge, Olsson, Tomas, Taylor, Bruce V., Sawcer, Stephen, Hafler, David A., Carrington, Mary, De Jager, Philip L., de Bakker, Paul I. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836799/ https://www.ncbi.nlm.nih.gov/pubmed/24278027 http://dx.doi.org/10.1371/journal.pgen.1003926

Ejemplares similares

A Major Histocompatibility Class I Locus Contributes to Multiple Sclerosis Susceptibility Independently from HLA-DRB1*15:01
por: Cree, Bruce A. C., et al.
Publicado: (2010)

HLA Diversity in the 1000 Genomes Dataset
por: Gourraud, Pierre-Antoine, et al.
Publicado: (2014)

HLA-E: A Novel Player for Histocompatibility
por: Kraemer, Thomas, et al.
Publicado: (2014)

The killer immunoglobulin-like receptor KIR3DL1 combination with HLA-Bw4 is protective against multiple sclerosis in African Americans
por: Hollenbach, Jill A., et al.
Publicado: (2016)

Strategies to work with HLA data in human populations for histocompatibility, clinical transplantation, epidemiology and population genetics: HLA-NET methodological recommendations
por: Sanchez-Mazas, A, et al.
Publicado: (2012)

T cell recognition of self-human histocompatibility leukocyte antigens (HLA)-DR peptides in context of syngeneic HLA-DR molecules
Publicado: (1992)

Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs
Publicado: (1996)

Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis
por: Hedström, Anna Karin, et al.
Publicado: (2014)

“HLA-C: evolution, epigenetics, and pathological implications in the major histocompatibility complex”
por: Velastegui, Erick, et al.
Publicado: (2023)

Identification of the Lateral Interaction Surfaces of Human Histocompatibility Leukocyte Antigen (HLA)-DM with HLA-DR1 by Formation of Tethered Complexes That Present Enhanced HLA-DM Catalysis
por: Stratikos, Efstratios, et al.
Publicado: (2002)

The Specificity of Peptides Bound to Human Histocompatibility Leukocyte Antigen (HLA)-B27 Influences the Prevalence of Arthritis in HLA-B27 Transgenic Rats
por: Zhou, Ming, et al.
Publicado: (1998)

Interaction between passive smoking and two HLA genes with regard to multiple sclerosis risk
por: Hedström, Anna Karin, et al.
Publicado: (2014)

Easy-HLA: a validated web application suite to reveal the full details of HLA typing
por: Geffard, Estelle, et al.
Publicado: (2020)

Breastfeeding is associated with reduced risk of multiple sclerosis in males, predominantly among HLA-DRB1*15:01 carriers
por: Hedström, AK, et al.
Publicado: (2020)

A second major histocompatibility complex susceptibility locus for multiple sclerosis
por: Yeo, Tai Wai, et al.
Publicado: (2007)

Hla-Dm Recognizes the Flexible Conformation of Major Histocompatibility Complex Class II
por: Chou, Chih-Ling, et al.
Publicado: (2000)

SNP‐HLA Reference Consortium (SHLARC): HLA and SNP data sharing for promoting MHC‐centric analyses in genomics
por: Vince, Nicolas, et al.
Publicado: (2020)

Modulation of the Major Histocompatibility Complex Class II–Associated Peptide Repertoire by Human Histocompatibility Leukocyte Antigen (Hla)-Do
por: van Ham, Marieke, et al.
Publicado: (2000)

Rapid Multiplex Genotyping of 20 HLA-A(*)02:01 Restricted Minor Histocompatibility Antigens
por: Romaniuk, Dmitrii S., et al.
Publicado: (2019)

Next-generation sequencing for HLA typing of class I loci
por: Erlich, Rachel L, et al.
Publicado: (2011)

Genetic variation within the HLA class III influences T1D susceptibility conferred by high risk HLA haplotypes
por: Valdes, Ana M, et al.
Publicado: (2010)

Mother−child histocompatibility and risk of rheumatoid arthritis and systemic lupus erythematosus among mothers
por: Cruz, Giovanna I., et al.
Publicado: (2019)

Receiver Operating Characteristic Analysis of HLA, CTLA4, and Insulin Genotypes for Type 1 Diabetes
por: Valdes, Ana M., et al.
Publicado: (2013)

Human histocompatibility determinants and virus antigens: effect of measles virus infection on HLA expression
Publicado: (1977)

Major Histocompatibility Complex and Hematopoietic Stem Cell Transplantation: Beyond the Classical HLA Polymorphism
por: Bertaina, Alice, et al.
Publicado: (2018)

Current HLA Investigations on SARS-CoV-2 and Perspectives
por: Douillard, Venceslas, et al.
Publicado: (2021)

Anchoring pockets in human histocompatibility complex leukocyte antigen (HLA) class I molecules: analysis of the conserved B ("45") pocket of HLA-B27
Publicado: (1992)

Patterns of Immunodominance in HIV-1–specific Cytotoxic T Lymphocyte Responses in Two Human Histocompatibility Leukocyte Antigens (HLA)-identical Siblings with HLA-A*0201 Are Influenced by Epitope Mutation
por: Goulder, P.J.R., et al.
Publicado: (1997)

HLA-C downregulation by HIV-1 adapts to host HLA genotype
por: Bachtel, Nathaniel D., et al.
Publicado: (2018)

Polymorphism of human minor histocompatibility antigens: T cell recognition of human minor histocompatibility peptides presented by HLA- B35 subtype molecules
Publicado: (1995)

Optimized Whole Genome Association Scanning for Discovery of HLA Class I-Restricted Minor Histocompatibility Antigens
por: Fuchs, Kyra J., et al.
Publicado: (2020)

Approaching Genetics Through the MHC Lens: Tools and Methods for HLA Research
por: Douillard, Venceslas, et al.
Publicado: (2021)

Tetrameric Complexes of Human Histocompatibility Leukocyte Antigen (HLA)-G Bind to Peripheral Blood Myelomonocytic Cells
por: Allan, David S.J., et al.
Publicado: (1999)

In Vivo Evidence for the Contribution of Human Histocompatibility Leukocyte Antigen (Hla)-Dq Molecules to the Development of Diabetes
por: Wen, Li, et al.
Publicado: (2000)

The interaction between smoking and HLA genes in multiple sclerosis: replication and refinement
por: Hedström, Anna Karin, et al.
Publicado: (2017)

HLA Class II Genotyping of African American Type 1 Diabetic Patients Reveals Associations Unique to African Haplotypes
por: Noble, Janelle A., et al.
Publicado: (2013)

Comprehensive analysis of the major histocompatibility complex in systemic sclerosis identifies differential HLA associations by clinical and serological subtypes
por: Acosta-Herrera, Marialbert, et al.
Publicado: (2021)

High Resolution Haplotype Analyses of Classical HLA Genes in Families With Multiple Sclerosis Highlights the Role of HLA-DP Alleles in Disease Susceptibility
por: Osoegawa, Kazutoyo, et al.
Publicado: (2021)

Dominant Sequences of Human Major Histocompatibility Complex Conserved Extended Haplotypes from HLA-DQA2 to DAXX
por: Larsen, Charles E., et al.
Publicado: (2014)

HLA Heterozygote Advantage against HIV-1 Is Driven by Quantitative and Qualitative Differences in HLA Allele-Specific Peptide Presentation
por: Arora, Jatin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_19kfjh5nh5e2nu66img7aa367e