Coordinate Nuclear Targeting of the FANCD2 and FANCI Proteins via a FANCD2 Nuclear Localization Signal

Fanconi anemia (FA) is a rare recessive disease, characterized by congenital defects, bone marrow failure, and increased cancer susceptibility. FA is caused by biallelic mutation of any one of sixteen genes. The protein products of these genes function cooperatively in the FA-BRCA pathway to repair...

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Detalles Bibliográficos
Autores principales: Boisvert, Rebecca A., Rego, Meghan A., Azzinaro, Paul A., Mauro, Maurizio, Howlett, Niall G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836817/
https://www.ncbi.nlm.nih.gov/pubmed/24278431
http://dx.doi.org/10.1371/journal.pone.0081387

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