Heparin Modulates the Endopeptidase Activity of Leishmania mexicana Cysteine Protease Cathepsin L-Like rCPB2.8

BACKGROUND: Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their attachment and internalization. Here,...

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Detalles Bibliográficos
Autores principales: Judice, Wagner A. S., Manfredi, Marcella A., Souza, Gerson P., Sansevero, Thiago M., Almeida, Paulo C., Shida, Cláudio S., Gesteira, Tarsis F., Juliano, Luiz, Westrop, Gareth D., Sanderson, Sanya J., Coombs, Graham H., Tersariol, Ivarne L. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836952/
https://www.ncbi.nlm.nih.gov/pubmed/24278253
http://dx.doi.org/10.1371/journal.pone.0080153

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