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Non-Invasive In Vivo Imaging of Near Infrared-labeled Transferrin in Breast Cancer Cells and Tumors Using Fluorescence Lifetime FRET
The conjugation of anti-cancer drugs to endogenous ligands has proven to be an effective strategy to enhance their pharmacological selectivity and delivery towards neoplasic tissues. Since cell proliferation has a strong requirement for iron, cancer cells express high levels of transferrin receptors...
Autores principales: | Abe, Ken, Zhao, Lingling, Periasamy, Ammasi, Intes, Xavier, Barroso, Margarida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836976/ https://www.ncbi.nlm.nih.gov/pubmed/24278268 http://dx.doi.org/10.1371/journal.pone.0080269 |
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