Amyloidosis, Synucleinopathy, and Prion Encephalopathy in a Neuropathic Lysosomal Storage Disease: The CNS-Biomarker Potential of Peripheral Blood

Mucopolysaccharidosis (MPS) IIIB is a devastating neuropathic lysosomal storage disease with complex pathology. This study identifies molecular signatures in peripheral blood that may be relevant to MPS IIIB pathogenesis using a mouse model. Genome-wide gene expression microarrays on pooled RNAs sho...

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Detalles Bibliográficos
Autores principales: Naughton, Bartholomew J., Duncan, F. Jason, Murrey, Darren, Ware, Tierra, Meadows, Aaron, McCarty, Douglas M., Fu, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836978/
https://www.ncbi.nlm.nih.gov/pubmed/24278249
http://dx.doi.org/10.1371/journal.pone.0080142

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