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The Cholinergic Anti-Inflammatory Pathway Delays TLR-Induced Skin Allograft Rejection in Mice: Cholinergic Pathway Modulates Alloreactivity
Activation of innate immunity through Toll-like receptors (TLR) can abrogate transplantation tolerance by revealing hidden T cell alloreactivity. Separately, the cholinergic anti-inflammatory pathway has the capacity to dampen macrophage activation and cytokine release during endotoxemia and ischemi...
Autores principales: | Sadis, Claude, Detienne, Sophie, Vokaer, Benoît, Charbonnier, Louis-Marie, Lemaître, Philippe, Spilleboudt, Chloé, Delbauve, Sandrine, Kubjak, Carole, Flamand, Véronique, Field, Kenneth A., Goldman, Michel, Benghiat, Fleur S., Le Moine, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836989/ https://www.ncbi.nlm.nih.gov/pubmed/24278228 http://dx.doi.org/10.1371/journal.pone.0079984 |
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