Cargando…

Highly Sensitive In Vivo Imaging of Trypanosoma brucei Expressing “Red-Shifted” Luciferase

BACKGROUND: Human African trypanosomiasis is caused by infection with parasites of the Trypanosoma brucei species complex, and threatens over 70 million people in sub-Saharan Africa. Development of new drugs is hampered by the limitations of current rodent models, particularly for stage II infection...

Descripción completa

Detalles Bibliográficos
Autores principales:	McLatchie, Alex P., Burrell-Saward, Hollie, Myburgh, Elmarie, Lewis, Michael D., Ward, Theresa H., Mottram, Jeremy C., Croft, Simon L., Kelly, John M., Taylor, Martin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836995/ https://www.ncbi.nlm.nih.gov/pubmed/24278497 http://dx.doi.org/10.1371/journal.pntd.0002571

Ejemplares similares

Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection
por: Lewis, Michael D, et al.
Publicado: (2014)

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1
por: Currier, Rachel B., et al.
Publicado: (2018)

A Panel of Trypanosoma brucei Strains Tagged with Blue and Red-Shifted Luciferases for Bioluminescent Imaging in Murine Infection Models
por: Van Reet, Nick, et al.
Publicado: (2014)

Trypanosoma brucei brucei: Endocytic recycling is important for mouse infectivity
por: Natesan, Senthil Kumar A., et al.
Publicado: (2011)

Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi
por: Parsons, Marilyn, et al.
Publicado: (2005)

In Vivo Imaging of Trypanosome-Brain Interactions and Development of a Rapid Screening Test for Drugs against CNS Stage Trypanosomiasis
por: Myburgh, Elmarie, et al.
Publicado: (2013)

Tracking autophagy during proliferation and differentiation of Trypanosoma brucei
por: Proto, William R., et al.
Publicado: (2014)

Cytokinesis in Bloodstream Stage Trypanosoma brucei Requires a Family of Katanins and Spastin
por: Benz, Corinna, et al.
Publicado: (2012)

Searching for novel cell cycle regulators in Trypanosoma brucei with an RNA interference screen
por: Monnerat, Séverine, et al.
Publicado: (2009)

Correction: Cytokinesis in Bloodstream Stage Trypanosoma brucei Requires a Family of Katanins and Spastin
por: Benz, Corinna, et al.
Publicado: (2012)

Role of the Trypanosoma brucei natural cysteine peptidase inhibitor ICP in differentiation and virulence
por: Santos, Camila C, et al.
Publicado: (2007)

Beetle luciferases with naturally red- and blue-shifted emission
por: Carrasco-López, César, et al.
Publicado: (2018)

Imaging of the host/parasite interplay in cutaneous leishmaniasis
por: Millington, Owain R., et al.
Publicado: (2010)

Trypanosoma brucei Metacaspase 4 Is a Pseudopeptidase and a Virulence Factor
por: Proto, William R., et al.
Publicado: (2011)

Trypanosoma brucei Polo-like kinase is essential for basal body duplication, kDNA segregation and cytokinesis
por: Hammarton, Tansy C, et al.
Publicado: (2007)

An Essential Signal Peptide Peptidase Identified in an RNAi Screen of Serine Peptidases of Trypanosoma brucei
por: Moss, Catherine X., et al.
Publicado: (2015)

HANS users manual
por: McLatchie, R C F
Publicado: (1980)

Red-shifted luciferase-luciferin pairs for enhanced bioluminescence imaging
por: Yeh, Hsien-Wei, et al.
Publicado: (2017)

RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse
por: Fernandez-Cortes, Fernando, et al.
Publicado: (2017)

Trypanosoma brucei rhodesiense Inhibitor of Cysteine Peptidase (ICP) Is Required for Virulence in Mice and to Attenuate the Inflammatory Response
por: Costa, Tatiana F. R., et al.
Publicado: (2022)

Regulators of Trypanosoma brucei Cell Cycle Progression and Differentiation Identified Using a Kinome-Wide RNAi Screen
por: Jones, Nathaniel G., et al.
Publicado: (2014)

A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei
por: Saldivia, Manuel, et al.
Publicado: (2021)

SUMOylation in Trypanosoma brucei
por: Klein, Cornelia Andrea, et al.
Publicado: (2013)

The Activity of Red Nigerian Propolis and Some of Its Components against Trypanosoma brucei and Trypanosoma congolense
por: Alenezi, Samya S., et al.
Publicado: (2023)

Inhibitor of serine peptidase 2 enhances Leishmania major survival in the skin through control of monocytes and monocyte-derived cells
por: Goundry, Amy, et al.
Publicado: (2018)

Trypanosoma evansi is alike to Trypanosoma brucei brucei in the subcellular localisation of glycolytic enzymes
por: Moreno, S Andrea, et al.
Publicado: (2015)

A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427
por: Sykes, Melissa L, et al.
Publicado: (2009)

A paradigm shift: The mitoproteomes of procyclic and bloodstream Trypanosoma brucei are comparably complex
por: Zíková, Alena, et al.
Publicado: (2017)

Evaluation of In Vitro Activity of Essential Oils against Trypanosoma brucei brucei and Trypanosoma evansi
por: Habila, Nathan, et al.
Publicado: (2010)

Evidence that transport of iron from the lysosome to the cytosol in African trypanosomes is mediated by a mucolipin orthologue
por: Taylor, Martin C, et al.
Publicado: (2013)

Cell cycle regulation in Trypanosoma brucei
por: Hammarton, Tansy C.
Publicado: (2007)

C-Terminal Mutants of Apolipoprotein L-I Efficiently Kill Both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense
por: Lecordier, Laurence, et al.
Publicado: (2009)

De Novo Genome Assembly Shows Genome Wide Similarity between Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense
por: Sistrom, Mark, et al.
Publicado: (2016)

The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei
por: Rojas, Federico, et al.
Publicado: (2017)

Repetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi
por: Obado, Samson O, et al.
Publicado: (2007)

An Essential Farnesylated Kinesin in Trypanosoma brucei
por: Engelson, Erin J., et al.
Publicado: (2011)

Golgi duplication in Trypanosoma brucei
por: He, Cynthia Y., et al.
Publicado: (2004)

Phylogeography and Taxonomy of Trypanosoma brucei
por: Balmer, Oliver, et al.
Publicado: (2011)

The nuclear proteome of Trypanosoma brucei
por: Goos, Carina, et al.
Publicado: (2017)

Signatures of hybridization in Trypanosoma brucei
por: Kay, Christopher, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fqas1t39rhjv82e3vmoqb04fh1