Maternal Treatment with Agonistic Autoantibodies against Type-1 Angiotensin II Receptor in Late Pregnancy Increases Apoptosis of Myocardial Cells and Myocardial Susceptibility to Ischemia-Reperfusion Injury in Offspring Rats

Epidemiological studies have demonstrated that offspring born to mothers preeclampsia (PE) are at increased risk for developing cardiovascular diseases after birth, but the underlying mechanism is unknown. Angiotensin II receptor type 1 autoantibody (AT1-AA), an agonist acting via activation of the...

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Detalles Bibliográficos
Autores principales: Jin, Zhu, Zhang, Wenhui, Yang, Hailiang, Wang, Xiaofang, Zheng, Yanqian, Zhang, Qiaoyan, Zhi, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837006/
https://www.ncbi.nlm.nih.gov/pubmed/24278308
http://dx.doi.org/10.1371/journal.pone.0080709

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