Conditional Hypovascularization and Hypoxia in Islets Do Not Overtly Influence Adult β-Cell Mass or Function

It is generally accepted that vascularization and oxygenation of pancreatic islets are essential for the maintenance of an optimal β-cell mass and function and that signaling by vascular endothelial growth factor (VEGF) is crucial for pancreas development, insulin gene expression/secretion, and (com...

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Detalles Bibliográficos
Autores principales: D'Hoker, Joke, De Leu, Nico, Heremans, Yves, Baeyens, Luc, Minami, Kohtaro, Ying, Cai, Lavens, Astrid, Chintinne, Marie, Stangé, Geert, Magenheim, Judith, Swisa, Avital, Martens, Geert, Pipeleers, Daniel, van de Casteele, Mark, Seino, Susumo, Keshet, Eli, Dor, Yuval, Heimberg, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837025/
https://www.ncbi.nlm.nih.gov/pubmed/23974922
http://dx.doi.org/10.2337/db12-1827

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