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Human Insulin Resistance Is Associated With Increased Plasma Levels of 12α-Hydroxylated Bile Acids

Bile acids (BAs) exert pleiotropic metabolic effects, and physicochemical properties of different BAs affect their function. In rodents, insulin regulates BA composition, in part by regulating the BA 12α-hydroxylase CYP8B1. However, it is unclear whether a similar effect occurs in humans. To address...

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Detalles Bibliográficos
Autores principales:	Haeusler, Rebecca A., Astiarraga, Brenno, Camastra, Stefania, Accili, Domenico, Ferrannini, Ele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837033/ https://www.ncbi.nlm.nih.gov/pubmed/23884887 http://dx.doi.org/10.2337/db13-0639

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