PPARα and Sirt1 Mediate Erythropoietin Action in Increasing Metabolic Activity and Browning of White Adipocytes to Protect Against Obesity and Metabolic Disorders

Erythropoietin (EPO) has shown beneficial effects in the regulation of obesity and metabolic syndrome; however, the detailed mechanism is still largely unknown. Here, we created mice with adipocyte-specific deletion of EPO receptor. These mice exhibited obesity and decreased glucose tolerance and in...

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Detalles Bibliográficos
Autores principales: Wang, Li, Teng, Ruifeng, Di, Lijun, Rogers, Heather, Wu, Hong, Kopp, Jeffrey B., Noguchi, Constance Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837041/
https://www.ncbi.nlm.nih.gov/pubmed/23990359
http://dx.doi.org/10.2337/db13-0518

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