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Effects of alcohol mixed with energy drink and alcohol alone on subjective intoxication

Recent studies suggest that the combination of caffeine-containing drinks together with alcohol might reduce the subjective feelings of alcohol intoxication—the so-called “masking effect”. In this study, we aimed to review the effects of alcohol in combination with caffeine or energy drink with spec...

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Autores principales: Ulbrich, Andrea, Hemberger, Sophie Helene, Loidl, Alexandra, Dufek, Stephanie, Pablik, Eleonore, Fodor, Sugarka, Herle, Marion, Aufricht, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837191/
https://www.ncbi.nlm.nih.gov/pubmed/24178765
http://dx.doi.org/10.1007/s00726-013-1603-0
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author Ulbrich, Andrea
Hemberger, Sophie Helene
Loidl, Alexandra
Dufek, Stephanie
Pablik, Eleonore
Fodor, Sugarka
Herle, Marion
Aufricht, Christoph
author_facet Ulbrich, Andrea
Hemberger, Sophie Helene
Loidl, Alexandra
Dufek, Stephanie
Pablik, Eleonore
Fodor, Sugarka
Herle, Marion
Aufricht, Christoph
author_sort Ulbrich, Andrea
collection PubMed
description Recent studies suggest that the combination of caffeine-containing drinks together with alcohol might reduce the subjective feelings of alcohol intoxication—the so-called “masking effect”. In this study, we aimed to review the effects of alcohol in combination with caffeine or energy drink with special focus on the “masking effect”. Fifty-two healthy male volunteers were analysed concerning breath alcohol concentration and subjective sensations of intoxication using a 18 item Visual Analogue Scale in a randomised, double-blinded, controlled, four treatments cross-over trial after consumption of (A) placebo, (B) alcohol (vodka 37.5 % at a dose of 46.5 g ethanol), (C) alcohol in combination with caffeine at a dose of 80 mg (equivalent to one 250 ml can of energy drink) and (D) alcohol in combination with energy drink at a dose of 250 ml (one can). Primary variables were headache, weakness, salivation and motor coordination. Out of four primary variables, weakness and motor coordination showed a statistically significant difference between alcohol and non-alcohol group, out of 14 secondary variables, five more variables (dizziness, alterations in sight, alterations in walking, agitation and alterations in speech) also showed significant differences due mainly to contrasts with the non-alcohol group. In none of these end points, could a statistically significant effect be found for the additional ingestion of energy drink or caffeine on the subjective feelings of alcohol intoxication. This within-subjects study does not confirm the presence of a “masking effect” when combining caffeine or energy drink with alcohol.
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spelling pubmed-38371912013-11-29 Effects of alcohol mixed with energy drink and alcohol alone on subjective intoxication Ulbrich, Andrea Hemberger, Sophie Helene Loidl, Alexandra Dufek, Stephanie Pablik, Eleonore Fodor, Sugarka Herle, Marion Aufricht, Christoph Amino Acids Original Article Recent studies suggest that the combination of caffeine-containing drinks together with alcohol might reduce the subjective feelings of alcohol intoxication—the so-called “masking effect”. In this study, we aimed to review the effects of alcohol in combination with caffeine or energy drink with special focus on the “masking effect”. Fifty-two healthy male volunteers were analysed concerning breath alcohol concentration and subjective sensations of intoxication using a 18 item Visual Analogue Scale in a randomised, double-blinded, controlled, four treatments cross-over trial after consumption of (A) placebo, (B) alcohol (vodka 37.5 % at a dose of 46.5 g ethanol), (C) alcohol in combination with caffeine at a dose of 80 mg (equivalent to one 250 ml can of energy drink) and (D) alcohol in combination with energy drink at a dose of 250 ml (one can). Primary variables were headache, weakness, salivation and motor coordination. Out of four primary variables, weakness and motor coordination showed a statistically significant difference between alcohol and non-alcohol group, out of 14 secondary variables, five more variables (dizziness, alterations in sight, alterations in walking, agitation and alterations in speech) also showed significant differences due mainly to contrasts with the non-alcohol group. In none of these end points, could a statistically significant effect be found for the additional ingestion of energy drink or caffeine on the subjective feelings of alcohol intoxication. This within-subjects study does not confirm the presence of a “masking effect” when combining caffeine or energy drink with alcohol. Springer Vienna 2013-11-01 2013 /pmc/articles/PMC3837191/ /pubmed/24178765 http://dx.doi.org/10.1007/s00726-013-1603-0 Text en © The Author(s) 2013 https://creativecommons.org/licenses/by/2.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Article
Ulbrich, Andrea
Hemberger, Sophie Helene
Loidl, Alexandra
Dufek, Stephanie
Pablik, Eleonore
Fodor, Sugarka
Herle, Marion
Aufricht, Christoph
Effects of alcohol mixed with energy drink and alcohol alone on subjective intoxication
title Effects of alcohol mixed with energy drink and alcohol alone on subjective intoxication
title_full Effects of alcohol mixed with energy drink and alcohol alone on subjective intoxication
title_fullStr Effects of alcohol mixed with energy drink and alcohol alone on subjective intoxication
title_full_unstemmed Effects of alcohol mixed with energy drink and alcohol alone on subjective intoxication
title_short Effects of alcohol mixed with energy drink and alcohol alone on subjective intoxication
title_sort effects of alcohol mixed with energy drink and alcohol alone on subjective intoxication
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837191/
https://www.ncbi.nlm.nih.gov/pubmed/24178765
http://dx.doi.org/10.1007/s00726-013-1603-0
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