Cancer Stem Cells in Pancreatic Cancer

Pancreatic cancer is an aggressive malignant solid tumor well-known by early metastasis, local invasion, resistance to standard chemo- and radiotherapy and poor prognosis. Increasing evidence indicates that pancreatic cancer is initiated and propagated by cancer stem cells (CSCs). Here we review the...

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Detalles Bibliográficos
Autores principales: Bao, Qi, Zhao, Yue, Renner, Andrea, Niess, Hanno, Seeliger, Hendrik, Jauch, Karl-Walter, Bruns, Christiane J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837327/
https://www.ncbi.nlm.nih.gov/pubmed/24281178
http://dx.doi.org/10.3390/cancers2031629
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author Bao, Qi
Zhao, Yue
Renner, Andrea
Niess, Hanno
Seeliger, Hendrik
Jauch, Karl-Walter
Bruns, Christiane J.
author_facet Bao, Qi
Zhao, Yue
Renner, Andrea
Niess, Hanno
Seeliger, Hendrik
Jauch, Karl-Walter
Bruns, Christiane J.
author_sort Bao, Qi
collection PubMed
description Pancreatic cancer is an aggressive malignant solid tumor well-known by early metastasis, local invasion, resistance to standard chemo- and radiotherapy and poor prognosis. Increasing evidence indicates that pancreatic cancer is initiated and propagated by cancer stem cells (CSCs). Here we review the current research results regarding CSCs in pancreatic cancer and discuss the different markers identifying pancreatic CSCs. This review will focus on metastasis, microRNA regulation and anti-CSC therapy in pancreatic cancer.
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spelling pubmed-38373272013-11-22 Cancer Stem Cells in Pancreatic Cancer Bao, Qi Zhao, Yue Renner, Andrea Niess, Hanno Seeliger, Hendrik Jauch, Karl-Walter Bruns, Christiane J. Cancers (Basel) Review Pancreatic cancer is an aggressive malignant solid tumor well-known by early metastasis, local invasion, resistance to standard chemo- and radiotherapy and poor prognosis. Increasing evidence indicates that pancreatic cancer is initiated and propagated by cancer stem cells (CSCs). Here we review the current research results regarding CSCs in pancreatic cancer and discuss the different markers identifying pancreatic CSCs. This review will focus on metastasis, microRNA regulation and anti-CSC therapy in pancreatic cancer. MDPI 2010-08-19 /pmc/articles/PMC3837327/ /pubmed/24281178 http://dx.doi.org/10.3390/cancers2031629 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an Open Access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Bao, Qi
Zhao, Yue
Renner, Andrea
Niess, Hanno
Seeliger, Hendrik
Jauch, Karl-Walter
Bruns, Christiane J.
Cancer Stem Cells in Pancreatic Cancer
title Cancer Stem Cells in Pancreatic Cancer
title_full Cancer Stem Cells in Pancreatic Cancer
title_fullStr Cancer Stem Cells in Pancreatic Cancer
title_full_unstemmed Cancer Stem Cells in Pancreatic Cancer
title_short Cancer Stem Cells in Pancreatic Cancer
title_sort cancer stem cells in pancreatic cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837327/
https://www.ncbi.nlm.nih.gov/pubmed/24281178
http://dx.doi.org/10.3390/cancers2031629
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AT seeligerhendrik cancerstemcellsinpancreaticcancer
AT jauchkarlwalter cancerstemcellsinpancreaticcancer
AT brunschristianej cancerstemcellsinpancreaticcancer

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