The role of microglia in adult hippocampal neurogenesis

Our view of microglia has dramatically changed in the last decade. From cells being “silent” in the healthy brain, microglia have emerged to be actively involved in several brain physiological functions including adult hippocampal neurogenesis, and cognitive and behavioral function. In light of rece...

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Detalles Bibliográficos
Autores principales: Gemma, Carmelina, Bachstetter, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837350/
https://www.ncbi.nlm.nih.gov/pubmed/24319411
http://dx.doi.org/10.3389/fncel.2013.00229
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author Gemma, Carmelina
Bachstetter, Adam D.
author_facet Gemma, Carmelina
Bachstetter, Adam D.
author_sort Gemma, Carmelina
collection PubMed
description Our view of microglia has dramatically changed in the last decade. From cells being “silent” in the healthy brain, microglia have emerged to be actively involved in several brain physiological functions including adult hippocampal neurogenesis, and cognitive and behavioral function. In light of recent discoveries revealing a role of microglia as important effectors of neuronal circuit reorganization, considerable attention has been focused on how microglia and hippocampal neurogenesis could be an interdependent phenomenon. In this review the role of microglia in the adult hippocampal neurogenesis under physiological condition is discussed.
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spelling pubmed-38373502013-12-06 The role of microglia in adult hippocampal neurogenesis Gemma, Carmelina Bachstetter, Adam D. Front Cell Neurosci Neuroscience Our view of microglia has dramatically changed in the last decade. From cells being “silent” in the healthy brain, microglia have emerged to be actively involved in several brain physiological functions including adult hippocampal neurogenesis, and cognitive and behavioral function. In light of recent discoveries revealing a role of microglia as important effectors of neuronal circuit reorganization, considerable attention has been focused on how microglia and hippocampal neurogenesis could be an interdependent phenomenon. In this review the role of microglia in the adult hippocampal neurogenesis under physiological condition is discussed. Frontiers Media S.A. 2013-11-22 /pmc/articles/PMC3837350/ /pubmed/24319411 http://dx.doi.org/10.3389/fncel.2013.00229 Text en Copyright © 2013 Gemma and Bachstetter. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Gemma, Carmelina
Bachstetter, Adam D.
The role of microglia in adult hippocampal neurogenesis
title The role of microglia in adult hippocampal neurogenesis
title_full The role of microglia in adult hippocampal neurogenesis
title_fullStr The role of microglia in adult hippocampal neurogenesis
title_full_unstemmed The role of microglia in adult hippocampal neurogenesis
title_short The role of microglia in adult hippocampal neurogenesis
title_sort role of microglia in adult hippocampal neurogenesis
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837350/
https://www.ncbi.nlm.nih.gov/pubmed/24319411
http://dx.doi.org/10.3389/fncel.2013.00229
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