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Cross-Linking as an Adjuvant Treatment for Tectonic Corneal Lamellar Graft Preparation

PURPOSE: To describe a new surgical approach for the tectonic reconstruction of the anterior ocular segment and the management of scleral and conjuctival melting. METHODS: Case series of patients demonstrating anterior segment anomalies, such as scleral and conjunctival melting. The anterior stromal...

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Autores principales: Kymionis, George D., Plaka, Argyro D., Diakonis, Vasilios F., Grentzelos, Michael A., Kontadakis, Georgios A., Mersinoglou, Andreana C., Detorakis, Efstathios T., Topouzis, Fotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837367/
https://www.ncbi.nlm.nih.gov/pubmed/24278090
http://dx.doi.org/10.2174/1874364101307010079
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author Kymionis, George D.
Plaka, Argyro D.
Diakonis, Vasilios F.
Grentzelos, Michael A.
Kontadakis, Georgios A.
Mersinoglou, Andreana C.
Detorakis, Efstathios T.
Topouzis, Fotis
author_facet Kymionis, George D.
Plaka, Argyro D.
Diakonis, Vasilios F.
Grentzelos, Michael A.
Kontadakis, Georgios A.
Mersinoglou, Andreana C.
Detorakis, Efstathios T.
Topouzis, Fotis
author_sort Kymionis, George D.
collection PubMed
description PURPOSE: To describe a new surgical approach for the tectonic reconstruction of the anterior ocular segment and the management of scleral and conjuctival melting. METHODS: Case series of patients demonstrating anterior segment anomalies, such as scleral and conjunctival melting. The anterior stromal part of a pre-cut corneal graft for Descemet’s stripping automated endothelial keratoplasty (DSAEK) was cross-linked with riboflavin and ultraviolet A irradiation and was used to cover scleral (scleral melting in a patient with necrotizing scleritis, one case) and conjuctival (dehiscence of the conjunctiva in patients with anti-glaucomatous valve exposure, two cases) areas. The endothelial part of all corneal grafts was used for DSAEK in patients with need of corneal endothelial transplantation. RESULTS: Repair of scleral and conjuctival melting was successful in all cases. No intra- or post- operative complications occured. Visual acuity of all patients remained stable during the follow up period. One year postoperatively the corneal graft remained in place and no signs of inflammation were evident, while all grafts were epithelialized. CONCLUSIONS: The use of cross-linked corneal graft for the tectonic reconstruction of the anterior ocular segment represents an adequate surgical approach for the management of scleral and conjuctival melting; while, at the same time it offers the advantage of using one corneal graft for two recipients.
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spelling pubmed-38373672013-11-25 Cross-Linking as an Adjuvant Treatment for Tectonic Corneal Lamellar Graft Preparation Kymionis, George D. Plaka, Argyro D. Diakonis, Vasilios F. Grentzelos, Michael A. Kontadakis, Georgios A. Mersinoglou, Andreana C. Detorakis, Efstathios T. Topouzis, Fotis Open Ophthalmol J Article PURPOSE: To describe a new surgical approach for the tectonic reconstruction of the anterior ocular segment and the management of scleral and conjuctival melting. METHODS: Case series of patients demonstrating anterior segment anomalies, such as scleral and conjunctival melting. The anterior stromal part of a pre-cut corneal graft for Descemet’s stripping automated endothelial keratoplasty (DSAEK) was cross-linked with riboflavin and ultraviolet A irradiation and was used to cover scleral (scleral melting in a patient with necrotizing scleritis, one case) and conjuctival (dehiscence of the conjunctiva in patients with anti-glaucomatous valve exposure, two cases) areas. The endothelial part of all corneal grafts was used for DSAEK in patients with need of corneal endothelial transplantation. RESULTS: Repair of scleral and conjuctival melting was successful in all cases. No intra- or post- operative complications occured. Visual acuity of all patients remained stable during the follow up period. One year postoperatively the corneal graft remained in place and no signs of inflammation were evident, while all grafts were epithelialized. CONCLUSIONS: The use of cross-linked corneal graft for the tectonic reconstruction of the anterior ocular segment represents an adequate surgical approach for the management of scleral and conjuctival melting; while, at the same time it offers the advantage of using one corneal graft for two recipients. Bentham Open 2013-10-30 /pmc/articles/PMC3837367/ /pubmed/24278090 http://dx.doi.org/10.2174/1874364101307010079 Text en © Kymionis et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Kymionis, George D.
Plaka, Argyro D.
Diakonis, Vasilios F.
Grentzelos, Michael A.
Kontadakis, Georgios A.
Mersinoglou, Andreana C.
Detorakis, Efstathios T.
Topouzis, Fotis
Cross-Linking as an Adjuvant Treatment for Tectonic Corneal Lamellar Graft Preparation
title Cross-Linking as an Adjuvant Treatment for Tectonic Corneal Lamellar Graft Preparation
title_full Cross-Linking as an Adjuvant Treatment for Tectonic Corneal Lamellar Graft Preparation
title_fullStr Cross-Linking as an Adjuvant Treatment for Tectonic Corneal Lamellar Graft Preparation
title_full_unstemmed Cross-Linking as an Adjuvant Treatment for Tectonic Corneal Lamellar Graft Preparation
title_short Cross-Linking as an Adjuvant Treatment for Tectonic Corneal Lamellar Graft Preparation
title_sort cross-linking as an adjuvant treatment for tectonic corneal lamellar graft preparation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837367/
https://www.ncbi.nlm.nih.gov/pubmed/24278090
http://dx.doi.org/10.2174/1874364101307010079
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