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Genetic transfer of fusion proteins effectively inhibits VCAM-1-mediated cell adhesion and transmigration via inhibition of cytoskeletal anchorage

The adhesion of leukocytes to endothelium plays a central role in the development of atherosclerosis and thus represents an attractive therapeutic target for anti-atherosclerotic therapies. Vascular cell adhesion molecule-1 (VCAM-1) mediates both the initial tethering and the firm adhesion of leukoc...

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Detalles Bibliográficos
Autores principales:	Hagemeyer, Christoph E, Ahrens, Ingo, Bassler, Nicole, Dschachutaschwili, Natia, Chen, Yung C, Eisenhardt, Steffen U, Bode, Christoph, Peter, Karlheinz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837607/ https://www.ncbi.nlm.nih.gov/pubmed/20414973 http://dx.doi.org/10.1111/j.1582-4934.2008.00409.x

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