Telomere attrition and genomic instability in xeroderma pigmentosum type-b deficient fibroblasts under oxidative stress

Xeroderma pigmentosum B (XPB/ERCC3/p89) is an ATP-dependent 3′→5′ directed DNA helicase involved in basal RNA transcription and the nucleotide excision repair (NER) pathway. While the role of NER in alleviating oxidative DNA damage has been acknowledged it remains poorly understood. To study the inv...

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Detalles Bibliográficos
Autores principales: Ting, Aloysius Poh Leong, Low, Grace Kah Mun, Gopalakrishnan, Kalpana, Hande, M Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837611/
https://www.ncbi.nlm.nih.gov/pubmed/19840190
http://dx.doi.org/10.1111/j.1582-4934.2009.00945.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837611/
https://www.ncbi.nlm.nih.gov/pubmed/19840190
http://dx.doi.org/10.1111/j.1582-4934.2009.00945.x

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