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Telomere attrition and genomic instability in xeroderma pigmentosum type-b deficient fibroblasts under oxidative stress
Xeroderma pigmentosum B (XPB/ERCC3/p89) is an ATP-dependent 3′→5′ directed DNA helicase involved in basal RNA transcription and the nucleotide excision repair (NER) pathway. While the role of NER in alleviating oxidative DNA damage has been acknowledged it remains poorly understood. To study the inv...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837611/ https://www.ncbi.nlm.nih.gov/pubmed/19840190 http://dx.doi.org/10.1111/j.1582-4934.2009.00945.x |