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A review on the molecular diagnostics of Lynch syndrome: a central role for the pathology laboratory
Lynch syndrome (LS) is caused by mutations in mismatch repair genes and is characterized by a high cumulative risk for the development of mainly colorectal carcinoma and endometrial carcinoma. Early detection of LS is important since surveillance can reduce morbidity and mortality. However, the diag...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837620/ https://www.ncbi.nlm.nih.gov/pubmed/19929944 http://dx.doi.org/10.1111/j.1582-4934.2009.00977.x |