Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010

Analysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains. Data suggest that the widespread use of this monovalent rotavi...

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Detalles Bibliográficos
Autores principales: Rose, Tatiana Lundgren, Marques da Silva, Marcelle Figueira, Goméz, Mariela Martinéz, Resque, Hugo Reis, Ichihara, Maria Yury Travassos, Volotão, Eduardo de Mello, Leite, José Paulo Gagliardi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2013
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837663/
https://www.ncbi.nlm.nih.gov/pubmed/24188273
http://dx.doi.org/10.3201/eid1911.121407
Descripción
Sumario:Analysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains. Data suggest that the widespread use of this monovalent rotavirus vaccine may introduce vaccine genes into circulating human rotaviruses or vice versa.

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