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Crystal Structure of Venezuelan Hemorrhagic Fever Virus Fusion Glycoprotein Reveals a Class 1 Postfusion Architecture with Extensive Glycosylation

Guanarito virus (GTOV) is an emergent and deadly pathogen. We present the crystal structure of the glycosylated GTOV fusion glycoprotein to 4.1-Å resolution in the postfusion conformation. Our structure reveals a classical six-helix bundle and presents direct verification that New World arenaviruses...

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Detalles Bibliográficos
Autores principales:	Parsy, Marie-Laure, Harlos, Karl, Huiskonen, Juha T., Bowden, Thomas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2013
Materias:	Structure and Assembly
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838125/ https://www.ncbi.nlm.nih.gov/pubmed/24049182 http://dx.doi.org/10.1128/JVI.02298-13

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