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Involvement of TGFβ-Induced Phosphorylation of the PTEN C-Terminus on TGFβ-Induced Acquisition of Malignant Phenotypes in Lung Cancer Cells

Transforming growth factor β (TGFβ) derived from the tumor microenvironment induces malignant phenotypes such as epithelial-mesenchymal transition (EMT) and aberrant cell motility in lung cancers. TGFβ-induced translocation of β-catenin from E-cadherin complexes into the cytoplasm is involved in the...

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Detalles Bibliográficos
Autores principales: Aoyama, Daisuke, Hashimoto, Naozumi, Sakamoto, Koji, Kohnoh, Takashi, Kusunose, Masaaki, Kimura, Motohiro, Ogata, Ryo, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Hasegawa, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838341/
https://www.ncbi.nlm.nih.gov/pubmed/24278390
http://dx.doi.org/10.1371/journal.pone.0081133