Cargando…

Investigating the Allosteric Regulation of YfiN from Pseudomonas aeruginosa: Clues from the Structure of the Catalytic Domain

Pseudomonas aeruginosa is responsible for a plethora of biofilm mediated chronic infections among which cystic fibrosis pneumonia is the most frightening. The long-term survival strategy of P. aeruginosa in the patients lungs is based on a fine balance of virulence vs dormant states and on genetic a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giardina, Giorgio, Paiardini, Alessandro, Fernicola, Silvia, Franceschini, Stefano, Rinaldo, Serena, Stelitano, Valentina, Cutruzzolà, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838380/ https://www.ncbi.nlm.nih.gov/pubmed/24278422 http://dx.doi.org/10.1371/journal.pone.0081324

Ejemplares similares

C-di-GMP Hydrolysis by Pseudomonas aeruginosa HD-GYP Phosphodiesterases: Analysis of the Reaction Mechanism and Novel Roles for pGpG
por: Stelitano, Valentina, et al.
Publicado: (2013)

Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
por: Li, Shanshan, et al.
Publicado: (2015)

Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy
por: Stelitano, Valentina, et al.
Publicado: (2013)

Multicellular String-Like Structure Formation by Salmonella Typhimurium Depends on Cellulose Production: Roles of Diguanylate Cyclases, YedQ and YfiN
por: Varghese, Alan, et al.
Publicado: (2020)

Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
por: Xu, Min, et al.
Publicado: (2016)

YfiBNR Mediates Cyclic di-GMP Dependent Small Colony Variant Formation and Persistence in Pseudomonas aeruginosa
por: Malone, Jacob G., et al.
Publicado: (2010)

The YfiBNR Signal Transduction Mechanism Reveals Novel Targets for the Evolution of Persistent Pseudomonas aeruginosa in Cystic Fibrosis Airways
por: Malone, Jacob G., et al.
Publicado: (2012)

Glucose Metabolism in the Progression of Prostate Cancer
por: Cutruzzolà, Francesca, et al.
Publicado: (2017)

Nutrient Sensing and Biofilm Modulation: The Example of L-arginine in Pseudomonas
por: Scribani Rossi, Chiara, et al.
Publicado: (2022)

The phosphodiesterase RmcA contributes to the adaptation of Pseudomonas putida to l-arginine
por: Scribani-Rossi, Chiara, et al.
Publicado: (2023)

Structure and metal-binding properties of PA4063, a novel player in periplasmic zinc trafficking by Pseudomonas aeruginosa
por: Fiorillo, Annarita, et al.
Publicado: (2021)

Structural Basis for the Peptidoglycan-Editing Activity of YfiH
por: Lee, Meng-Sheng, et al.
Publicado: (2022)

Importance of amino acids in brain parenchyma invasion by cancer cells
por: Paone, Alessio, et al.
Publicado: (2021)

SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
por: Paone, A, et al.
Publicado: (2014)

Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis
por: Giardina, Giorgio, et al.
Publicado: (2017)

Studying GGDEF Domain in the Act: Minimize Conformational Frustration to Prevent Artefacts
por: Mantoni, Federico, et al.
Publicado: (2021)

YfiB: An Outer Membrane Protein Involved in the Virulence of Shigella flexneri
por: Sen, Tanuka, et al.
Publicado: (2022)

Catalytic process of anhydro-N-acetylmuramic acid kinase from Pseudomonas aeruginosa
por: El-Araby, Amr M., et al.
Publicado: (2023)

Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosa
por: Cukier, Cyprian D., et al.
Publicado: (2013)

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells
por: Marani, Marina, et al.
Publicado: (2015)

Protein Interaction Networks of Catalytically Active and Catalytically Inactive PqsE in Pseudomonas aeruginosa
por: Taylor, Isabelle R., et al.
Publicado: (2022)

Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments
por: Monti, Michele, et al.
Publicado: (2021)

The Emerging Role of Amino Acids of the Brain Microenvironment in the Process of Metastasis Formation
por: Cutruzzolà, Francesca, et al.
Publicado: (2021)

Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
por: Spizzichino, Sharon, et al.
Publicado: (2021)

The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism
por: Guiducci, Giulia, et al.
Publicado: (2019)

Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity
por: Bouzidi, Amani, et al.
Publicado: (2020)

The antiactivator FleN uses an allosteric mechanism to regulate σ(54)-dependent expression of flagellar genes in Pseudomonas aeruginosa
por: Chanchal,, et al.
Publicado: (2021)

Vesiculation from Pseudomonas aeruginosa under SOS
por: Maredia, Reshma, et al.
Publicado: (2012)

Crystal structure and catalytic mechanism of the essential m(1)G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa
por: Jaroensuk, Juthamas, et al.
Publicado: (2019)

Resistance of Pseudomonas Aeruginosa
por: Graevenitz, Alexander Von
Publicado: (1977)

Pseudomonas aeruginosa Biofilms
por: Thi, Minh Tam Tran, et al.
Publicado: (2020)

The Impact of the Virulence of Pseudomonas aeruginosa Isolated from Dogs
por: de Sousa, Telma, et al.
Publicado: (2023)

The prevalence of Pseudomonas aeruginosa and multidrug resistant Pseudomonas aeruginosa in healthy captive ophidian
por: Sala, Andrea, et al.
Publicado: (2019)

Active immunization with Pseudomonas aeruginosa vaccine protects mice from secondary Pseudomonas aeruginosa challenge post-influenza virus infection
por: Wu, Xiaofeng, et al.
Publicado: (2023)

Phosphofructokinases A and B from Mycobacterium tuberculosis Display Different Catalytic Properties and Allosteric Regulation
por: Snášel, Jan, et al.
Publicado: (2021)

The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease
por: Kosinski, Richard, et al.
Publicado: (2022)

Clues from hypercalcaemia
por: Nicholson, S, et al.
Publicado: (2002)

Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1
por: Mohanty, Biswaranjan, et al.
Publicado: (2017)

Kinetic characterisation of arylamine N-acetyltransferase from Pseudomonas aeruginosa
por: Westwood, Isaac M, et al.
Publicado: (2007)

A functional type I topoisomerase from Pseudomonas aeruginosa
por: Jain, Teesta, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_lglfmkjmmiu567fk6riv594i0d