Cargando…
HDAC4 Does Not Act as a Protein Deacetylase in the Postnatal Murine Brain In Vivo
Reversible protein acetylation provides a central mechanism for controlling gene expression and cellular signaling events. It is governed by the antagonistic commitment of two enzymes families: the histone acetyltransferases (HATs) and the histone deacetylases (HDACs). HDAC4, like its class IIa coun...
Autores principales: | Mielcarek, Michal, Seredenina, Tamara, Stokes, Matthew P., Osborne, Georgina F., Landles, Christian, Inuabasi, Linda, Franklin, Sophie A., Silva, Jeffrey C., Luthi-Carter, Ruth, Beaumont, Vahri, Bates, Gillian P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838388/ https://www.ncbi.nlm.nih.gov/pubmed/24278330 http://dx.doi.org/10.1371/journal.pone.0080849 |
Ejemplares similares
-
HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration
por: Mielcarek, Michal, et al.
Publicado: (2013) -
The Huntington's Disease-Related Cardiomyopathy Prevents a Hypertrophic Response in the R6/2 Mouse Model
por: Mielcarek, Michal, et al.
Publicado: (2014) -
Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease
por: Mielcarek, Michal, et al.
Publicado: (2014) -
Decreased Striatal RGS2 Expression Is Neuroprotective in Huntington's Disease (HD) and Exemplifies a Compensatory Aspect of HD-Induced Gene Regulation
por: Seredenina, Tamara, et al.
Publicado: (2011) -
Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice
por: Bryant, Dale T., et al.
Publicado: (2017)