Placental Disease and the Maternal Syndrome of Preeclampsia: Missing Links?

Preeclampsia remains a significant obstetric risk worldwide. The pathophysiology of preeclampsia is complex, with multiple stages involving maladaptations in both placental and maternal physiology. The placenta links the pre-clinical stage of impaired remodeling of the uterine vasculature, occurring...

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Detalles Bibliográficos
Autores principales: Tannetta, Dionne, Sargent, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Preeclampsia (VD Garovic, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838579/
https://www.ncbi.nlm.nih.gov/pubmed/24108542
http://dx.doi.org/10.1007/s11906-013-0395-7
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author Tannetta, Dionne
Sargent, Ian
author_facet Tannetta, Dionne
Sargent, Ian
author_sort Tannetta, Dionne
collection PubMed
description Preeclampsia remains a significant obstetric risk worldwide. The pathophysiology of preeclampsia is complex, with multiple stages involving maladaptations in both placental and maternal physiology. The placenta links the pre-clinical stage of impaired remodeling of the uterine vasculature, occurring in early pregnancy, to the later clinical stages characterised by the maternal syndrome of hypertension and proteinuria. This review focuses on some of the recent candidates for the missing links in this process.
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spelling pubmed-38385792013-12-02 Placental Disease and the Maternal Syndrome of Preeclampsia: Missing Links? Tannetta, Dionne Sargent, Ian Curr Hypertens Rep Preeclampsia (VD Garovic, Section Editor) Preeclampsia remains a significant obstetric risk worldwide. The pathophysiology of preeclampsia is complex, with multiple stages involving maladaptations in both placental and maternal physiology. The placenta links the pre-clinical stage of impaired remodeling of the uterine vasculature, occurring in early pregnancy, to the later clinical stages characterised by the maternal syndrome of hypertension and proteinuria. This review focuses on some of the recent candidates for the missing links in this process. Springer US 2013-10-10 2013 /pmc/articles/PMC3838579/ /pubmed/24108542 http://dx.doi.org/10.1007/s11906-013-0395-7 Text en © The Author(s) 2013 https://creativecommons.org/licenses/by-nc/2.0/ Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Preeclampsia (VD Garovic, Section Editor)
Tannetta, Dionne
Sargent, Ian
Placental Disease and the Maternal Syndrome of Preeclampsia: Missing Links?
title Placental Disease and the Maternal Syndrome of Preeclampsia: Missing Links?
title_full Placental Disease and the Maternal Syndrome of Preeclampsia: Missing Links?
title_fullStr Placental Disease and the Maternal Syndrome of Preeclampsia: Missing Links?
title_full_unstemmed Placental Disease and the Maternal Syndrome of Preeclampsia: Missing Links?
title_short Placental Disease and the Maternal Syndrome of Preeclampsia: Missing Links?
title_sort placental disease and the maternal syndrome of preeclampsia: missing links?
topic Preeclampsia (VD Garovic, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838579/
https://www.ncbi.nlm.nih.gov/pubmed/24108542
http://dx.doi.org/10.1007/s11906-013-0395-7
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