Kv7 potassium channel activation with ICA-105665 reduces photoparoxysmal EEG responses in patients with epilepsy

Purpose To assess the effects of ICA-105665, an agonist of neuronal Kv7 potassium channels, on epileptiform EEG discharges, evoked by intermittent photic stimulation (IPS), the so-called photoparoxysmal responses (PPRs) in patients with epilepsy. Methods Male and female patients aged 18–60 years wit...

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Detalles Bibliográficos
Autores principales: Kasteleijn-Nolst Trenité, Dorotheé G A, Biton, Victor, French, Jacqueline A, Abou-Khalil, Bassel, Rosenfeld, William E, Diventura, Bree, Moore, Elizabeth L, Hetherington, Seth V, Rigdon, Greg C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Full-Length Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838622/
https://www.ncbi.nlm.nih.gov/pubmed/23692516
http://dx.doi.org/10.1111/epi.12224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838622/
https://www.ncbi.nlm.nih.gov/pubmed/23692516
http://dx.doi.org/10.1111/epi.12224

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