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In vitro protein binding of liraglutide in human plasma determined by reiterated stepwise equilibrium dialysis

Liraglutide is a human glucagon-like peptide-1 (GLP-1) analogue approved for the treatment of type 2 diabetes. It is based on human GLP-1 with the addition of a 16-carbon fatty acid, which facilitates binding to plasma proteins, thus prolonging the elimination half-life and allowing once-daily admin...

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Detalles Bibliográficos
Autores principales:	Plum, Anne, Jensen, Lisbeth Bjerring, Kristensen, Jesper Bøggild
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Subscription Services, Inc., A Wiley Company 2013
Materias:	Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838623/ https://www.ncbi.nlm.nih.gov/pubmed/23853127 http://dx.doi.org/10.1002/jps.23648

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