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Developmental lineage priming in Dictyostelium by heterogeneous Ras activation

In cell culture, genetically identical cells often exhibit heterogeneous behavior, with only ‘lineage primed’ cells responding to differentiation inducing signals. It has recently been proposed that such heterogeneity exists during normal embryonic development to allow position independent patternin...

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Detalles Bibliográficos
Autores principales: Chattwood, Alex, Nagayama, Koki, Bolourani, Parvin, Harkin, Lauren, Kamjoo, Marzieh, Weeks, Gerald, Thompson, Christopher RL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838634/
https://www.ncbi.nlm.nih.gov/pubmed/24282234
http://dx.doi.org/10.7554/eLife.01067