Cargando…

Production and Characterization of Recombinant Light Chain and Carboxyterminal Heavy Chain Fragments of Tetanus Toxin

BACKGROUND: Light chain (LC) and heavy chain carboxyterminal subdomain (H(CC)) fragments are the most important parts of tetanus neurotoxin (TeNT) which play key roles in toxicity and binding of TeNT, respectively. In the present study, these two fragments were cloned and expressed in a prokaryotic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yousefi, Mehdi, Khosravi-Eghbal, Roya, Hemmati, Azam, Shokri, Fazel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Avicenna Research Institute 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838766/ https://www.ncbi.nlm.nih.gov/pubmed/24285996

Ejemplares similares

Tetanus Toxin cis-Loop Contributes to Light-Chain Translocation
por: Zuverink, Madison, et al.
Publicado: (2020)

Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease
por: Herrando-Grabulosa, Mireia, et al.
Publicado: (2020)

Vaccination of Rabbits with a Cholera Conjugate Vaccine Comprising O-Specific Polysaccharide and a Recombinant Fragment of Tetanus Toxin Heavy Chain Induces Protective Immune Responses against Vibrio cholerae O1
por: Kelly, Meagan, et al.
Publicado: (2023)

Tetanus Toxin C-Fragment: The Courier and the Cure?
por: Toivonen, Janne M., et al.
Publicado: (2010)

The light chain of tetanus toxin bound to arginine-rich cell-penetrating peptide inhibits cortical reaction in mouse oocytes
por: Klinsky, Omar G., et al.
Publicado: (2023)

Heavy Chains: Synthesis, Reactivity and Decomposition of Interpnictogen Chains with Terminal Diaryl Bismuth Fragments
por: Dunaj, Tobias, et al.
Publicado: (2022)

Radical-Mediated Enzymatic Carbon Chain Fragmentation-Recombination
por: Zhang, Qi, et al.
Publicado: (2011)

Characterisation of a panel of anti-tetanus toxin single-chain Fvs reveals cooperative binding
por: Scott, Nathan, et al.
Publicado: (2010)

Botulinum Neurotoxin Heavy Chain Belt as an Intramolecular Chaperone for the Light Chain
por: Brunger, Axel T, et al.
Publicado: (2007)

Epitope Mapping of Human HER2 Specific Mouse Monoclonal Antibodies Using Recombinant Extracellular Subdomains
por: Ghatar, Reza Hosseini, et al.
Publicado: (2017)

INDEPENDENT SYNTHESIS OF LIGHT AND HEAVY CHAINS : Quantitation of Light-Chain Production by Mouse Myeloma Variants
por: Laskov, Reuven, et al.
Publicado: (1974)

Heavy chain–only antibodies are spontaneously produced in light chain–deficient mice
por: Zou, Xiangang, et al.
Publicado: (2007)

Defective Kinesin Heavy Chain Behavior in Mouse Kinesin Light Chain Mutants
por: Rahman, Amena, et al.
Publicado: (1999)

Tetanus Toxin Fragment C: Structure, Drug Discovery Research and Production
por: Bayart, Caroline, et al.
Publicado: (2022)

A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice
por: Sayeed, Md. Abu, et al.
Publicado: (2015)

Dynein Modifiers in C. elegans: Light Chains Suppress Conditional Heavy Chain Mutants
por: O'Rourke, Sean M, et al.
Publicado: (2007)

Immunoglobulin heavy chain and binding protein complexes are dissociated in vivo by light chain addition
Publicado: (1990)

Recombination may occur in the absence of transcription in the immunoglobulin heavy chain recombination centre
por: Oudinet, Chloé, et al.
Publicado: (2020)

Fragment C of Tetanus Toxin: New Insights into Its Neuronal Signaling Pathway
por: Calvo, Ana C., et al.
Publicado: (2012)

Synthesis of myosin heavy and light chains in muscle cultures
Publicado: (1975)

Tetanus Toxin and Antitoxin
por: McFarland, Joseph, et al.
Publicado: (1899)

Tetanus Toxin and Antitoxin
por: McFarland, Joseph, et al.
Publicado: (1899)

Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent
por: Glater, Elizabeth E., et al.
Publicado: (2006)

Axonemal dynein light chain-1 locates at the microtubule-binding domain of the γ heavy chain
por: Ichikawa, Muneyoshi, et al.
Publicado: (2015)

Dictyostelium myosin: characterization of chymotryptic fragments and localization of the heavy-chain phosphorylation site
Publicado: (1981)

RECOMBINATION OF HEAVY AND LIGHT CHAINS OF HUMAN γA-MYELOMA PROTEINS: FORMATION OF HYBRID MOLECULES AND CONFIGURATIONAL SPECIFICITY
por: Prendergast, Robert A., et al.
Publicado: (1966)

Tetanus toxin fragment C fused to flagellin makes a potent mucosal vaccine
por: Lee, Shee Eun, et al.
Publicado: (2015)

Tetanus toxin fragments and Bcl-2 fusion proteins: cytoprotection and retrograde axonal migration
por: Watanabe, Yasuhiro, et al.
Publicado: (2018)

Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo
por: Netzahualcoyotzi, Citlalli, et al.
Publicado: (2018)

Neuroprotective Fragment C of Tetanus Toxin Modulates IL-6 in an ALS Mouse Model
por: Moreno-Martinez, Laura, et al.
Publicado: (2020)

Confocal Endomicroscopy of Neuromuscular Junctions Stained with Physiologically Inert Protein Fragments of Tetanus Toxin
por: Roesl, Cornelia, et al.
Publicado: (2021)

HEAVY AND LIGHT CHAIN ALLOTYPIC MARKERS ON RABBIT HOMOCYTOTROPIC ANTIBODY
por: Kindt, T. J., et al.
Publicado: (1969)

Chain drugstores: Opportunities and Threats
por: Mohammadzadeh, Mehdi, et al.
Publicado: (2014)

Regulation of motor activity of ciliary outer-arm dynein by the light chain 1; Implications from the structure of the light chain bound to the microtubule-binding domain of the heavy chain
por: Yagi, Toshiki, et al.
Publicado: (2023)

The Immunogenicity of the C Fragment of Tetanus Neurotoxin in Production of Tetanus Antitoxin
por: Yu, Rui, et al.
Publicado: (2018)

The Effect of Cysteine on Tetanus Toxin
por: Cowles, Philip B.
Publicado: (1936)

Fragment C Domain of Tetanus Toxin Mitigates Methamphetamine Neurotoxicity and Its Motor Consequences in Mice
por: Mendieta, Liliana, et al.
Publicado: (2016)

The Pneumococcal Polysaccharide-Tetanus Toxin Native C-Fragment Conjugate Vaccine: The Carrier Effect and Immunogenicity
por: Yu, Rui, et al.
Publicado: (2020)

Expression of heavy chain‐only antibodies can support B‐cell development in light chain knockout chickens
por: Schusser, Benjamin, et al.
Publicado: (2016)

Optimization of Heavy Chain and Light Chain Signal Peptides for High Level Expression of Therapeutic Antibodies in CHO Cells
por: Haryadi, Ryan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_n4uejca9992r51sa946qutgj7p