Improved scFv Anti-HIV-1 p17 Binding Affinity Guided from the Theoretical Calculation of Pairwise Decomposition Energies and Computational Alanine Scanning

Computational approaches have been used to evaluate and define important residues for protein-protein interactions, especially antigen-antibody complexes. In our previous study, pairwise decomposition of residue interaction energies of single chain Fv with HIV-1 p17 epitope variants has indicated th...

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Detalles Bibliográficos
Autores principales: Tue-ngeun, Panthip, Kodchakorn, Kanchanok, Nimmanpipug, Piyarat, Lawan, Narin, Nangola, Sawitree, Tayapiwatana, Chatchai, Rahman, Noorsaadah Abdul, Zain, Sharifuddin Md., Lee, Vannajan Sanghiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838816/
https://www.ncbi.nlm.nih.gov/pubmed/24308004
http://dx.doi.org/10.1155/2013/713585

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