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Threading the barrel of the RNA exosome

In eukaryotes, the exosome complex degrades RNA backbones and plays key roles in RNA processing and surveillance. It was predicted that RNA substrates are threaded through a central channel. This pathway is conserved between eukaryotic and archaeal complexes, even though nuclease activity was lost f...

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Detalles Bibliográficos
Autores principales: Schneider, Claudia, Tollervey, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Trends Journals 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838930/
https://www.ncbi.nlm.nih.gov/pubmed/23910895
http://dx.doi.org/10.1016/j.tibs.2013.06.013

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