Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya

Early identification of causal genetic variants underlying antimalarial drug resistance could provide robust epidemiological tools for timely public health interventions. Using a novel natural genetics strategy for mapping novel candidate genes we analyzed >75,000 high quality single nucleotide p...

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Detalles Bibliográficos
Autores principales: Borrmann, Steffen, Straimer, Judith, Mwai, Leah, Abdi, Abdirahman, Rippert, Anja, Okombo, John, Muriithi, Steven, Sasi, Philip, Kortok, Moses Mosobo, Lowe, Brett, Campino, Susana, Assefa, Samuel, Auburn, Sarah, Manske, Magnus, Maslen, Gareth, Peshu, Norbert, Kwiatkowski, Dominic P., Marsh, Kevin, Nzila, Alexis, Clark, Taane G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839035/
https://www.ncbi.nlm.nih.gov/pubmed/24270944
http://dx.doi.org/10.1038/srep03318

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