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Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya
Early identification of causal genetic variants underlying antimalarial drug resistance could provide robust epidemiological tools for timely public health interventions. Using a novel natural genetics strategy for mapping novel candidate genes we analyzed >75,000 high quality single nucleotide p...
Autores principales: | Borrmann, Steffen, Straimer, Judith, Mwai, Leah, Abdi, Abdirahman, Rippert, Anja, Okombo, John, Muriithi, Steven, Sasi, Philip, Kortok, Moses Mosobo, Lowe, Brett, Campino, Susana, Assefa, Samuel, Auburn, Sarah, Manske, Magnus, Maslen, Gareth, Peshu, Norbert, Kwiatkowski, Dominic P., Marsh, Kevin, Nzila, Alexis, Clark, Taane G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839035/ https://www.ncbi.nlm.nih.gov/pubmed/24270944 http://dx.doi.org/10.1038/srep03318 |
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