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MSI-Testing in Hereditary Non-Polyposis Colorectal Carcinoma (HNPCC)

Genomic instability at simple repeated sequences, termed microsatellite instability (MSI), plays an important role in the analysis of sporadic and hereditary colon cancers. In hereditary non-polyposis colorectal cancer syndrome (HNPCC) more than 90% of cases show MSI, whereas only 10–15% of sporadic...

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Detalles Bibliográficos
Autores principales: Müller, Annegret, Edmonston, Tina Bocker, Dietmaier, Wolfgang, Büttner, Reinhard, Fishel, Richard, Rüschoff, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839272/
https://www.ncbi.nlm.nih.gov/pubmed/15528788
http://dx.doi.org/10.1155/2004/343976