HDAC Inhibition by LBH589 Affects Phenotype and Function of Human Myeloid Dendritic Cells

LBH589 is a novel pan-HDAC inhibitor which has potent antitumor activity in multiple myeloma and other hematologic malignancies. However, its impact on immune system has not been defined. We here evaluated the effects of LBH589 on human myeloid dendritic cells (DCs) at clinically relevant concentrat...

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Detalles Bibliográficos
Autores principales: Song, W, Tai, Y-T, Tian, Z, Hideshima, T, Chauhan, D, Nanjappa, P, Exley, M A, Anderson, K C, Munshi, N C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839585/
https://www.ncbi.nlm.nih.gov/pubmed/21102427
http://dx.doi.org/10.1038/leu.2010.244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839585/
https://www.ncbi.nlm.nih.gov/pubmed/21102427
http://dx.doi.org/10.1038/leu.2010.244

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