Cargando…

Cyclic Phosphatidic Acid Stimulates cAMP Production and Inhibits Growth in Human Colon Cancer Cells

Colon cancer is a malignancy that develops in colon and rectal tissues. The prognosis for metastatic colon cancer remains poor, and novel therapeutic options are required to reduce colon cancer mortality. Recently, intracellular cAMP levels have been suggested to influence the behavior of cancer cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsukahara, Tamotsu, Matsuda, Yoshikazu, Haniu, Hisao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839875/ https://www.ncbi.nlm.nih.gov/pubmed/24282571 http://dx.doi.org/10.1371/journal.pone.0081139

Ejemplares similares

Cyclic Phosphatidic Acid Inhibits Alkyl-Glycerophosphate-Induced Downregulation of Histone Deacetylase 2 Expression and Suppresses the Inflammatory Response in Human Coronary Artery Endothelial Cells
por: Tsukahara, Tamotsu, et al.
Publicado: (2014)

PTB-Associated Splicing Factor (PSF) Is a PPARγ-Binding Protein and Growth Regulator of Colon Cancer Cells
por: Tsukahara, Tamotsu, et al.
Publicado: (2013)

Release of Cyclic Phosphatidic Acid from Gelatin-based Hydrogels Inhibit Colon Cancer Cell Growth and Migration
por: Tsukahara, Tamotsu, et al.
Publicado: (2012)

PSF Knockdown Enhances Apoptosis via Downregulation of LC3B in Human Colon Cancer Cells
por: Tsukahara, Tamotsu, et al.
Publicado: (2013)

Heart-type fatty-acid-binding protein (FABP3) is a lysophosphatidic acid-binding protein in human coronary artery endothelial cells
por: Tsukahara, Ryoko, et al.
Publicado: (2014)

Porcine liver decomposition product-derived lysophospholipids promote microglial activation in vitro
por: Tsukahara, Tamotsu, et al.
Publicado: (2020)

PPARγ Networks in Cell Signaling: Update and Impact of Cyclic Phosphatidic Acid
por: Tsukahara, Tamotsu
Publicado: (2013)

Therapeutic Potential of Porcine Liver Decomposition Product: New Insights and Perspectives for Microglia-Mediated Neuroinflammation in Neurodegenerative Diseases
por: Tsukahara, Tamotsu, et al.
Publicado: (2020)

The PTB-Associated Splicing Factor/Peroxisome Proliferator-Activated Receptor Gamma Axis Regulates Autophagosome Formation in Human Pancreatic Cancer Cells
por: Tsukahara, Tamotsu, et al.
Publicado: (2015)

Lysophospholipid-Related Diseases and PPARγ Signaling Pathway
por: Tsukahara, Tamotsu, et al.
Publicado: (2017)

Lysophosphatidic Acid Stimulates MCP-1 Secretion from C2C12 Myoblast
por: Tsukahara, Tamotsu, et al.
Publicado: (2012)

A Review of Cyclic Phosphatidic Acid and Other Potential Therapeutic Targets for Treating Osteoarthritis
por: Tsukahara, Tamotsu, et al.
Publicado: (2023)

Lysophospholipids: A Potential Drug Candidates for Neurodegenerative Disorders
por: Karaki, Tatsuya, et al.
Publicado: (2022)

Cyclic phosphatidic acid relieves osteoarthritis symptoms
por: Gotoh, Mari, et al.
Publicado: (2014)

The Role of Autophagy as a Mechanism of Toxicity Induced by Multi-Walled Carbon Nanotubes in Human Lung Cells
por: Tsukahara, Tamotsu, et al.
Publicado: (2014)

Cyclic 3', 5'-AMP relay dictyostelium discoideum. V. Adaptation of the cAMP signaling response during cAMP stimulation
por: Dinauer, M, et al.
Publicado: (1980)

Cyclic 3', 5'-AMP relay in dictyostelium discoideum. IV. Recovery of the cAMP signaling response after adaptation to cAMP
por: Dinauer, M, et al.
Publicado: (1980)

Suppression of Virulence of Toxigenic Vibrio cholerae by Anethole through the Cyclic AMP (cAMP)-cAMP Receptor Protein Signaling System
por: Zahid, M. Shamim Hasan, et al.
Publicado: (2015)

GDE7 produces cyclic phosphatidic acid in the ER lumen functioning as a lysophospholipid mediator
por: Kitakaze, Keisuke, et al.
Publicado: (2023)

Cyclic 3',5'-AMP relay in Dictyostelium discoideum III. The relationship of cAMP synthesis and secretion during the cAMP signaling response
Publicado: (1980)

Direct regulation of the natural competence regulator gene tfoX by cyclic AMP (cAMP) and cAMP receptor protein (CRP) in Vibrios
por: Wu, Rui, et al.
Publicado: (2015)

Endocytosis of Multiwalled Carbon Nanotubes in Bronchial Epithelial and Mesothelial Cells
por: Maruyama, Kayo, et al.
Publicado: (2015)

The Dispersion State of Tangled Multi-Walled Carbon Nanotubes Affects Their Cytotoxicity
por: Kuroda, Chika, et al.
Publicado: (2016)

Nonanal Stimulates Growth Factors via Cyclic Adenosine Monophosphate (cAMP) Signaling in Human Hair Follicle Dermal Papilla Cells
por: Park, Soyoon, et al.
Publicado: (2020)

Targeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid
por: Altman, Molly K, et al.
Publicado: (2010)

“cAMP Sponge”: A Buffer for Cyclic Adenosine 3′, 5′-Monophosphate
por: Lefkimmiatis, Konstantinos, et al.
Publicado: (2009)

Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating disease
por: Yamamoto, Shinji, et al.
Publicado: (2017)

2-Carba cyclic phosphatidic acid inhibits lipopolysaccharide-induced prostaglandin E2 production in a human macrophage cell line
por: Shibaike, Yuki, et al.
Publicado: (2019)

Cyclic Nucleotide-Specific Optogenetics Highlights Compartmentalization of the Sperm Flagellum into cAMP Microdomains
por: Raju, Diana N., et al.
Publicado: (2019)

Biological responses according to the shape and size of carbon nanotubes in BEAS-2B and MESO-1 cells
por: Haniu, Hisao, et al.
Publicado: (2014)

Leptin interferes with 3',5'-Cyclic Adenosine Monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells
por: Lin, Qing, et al.
Publicado: (2009)

Carvone Decreases Melanin Content by Inhibiting Melanoma Cell Proliferation via the Cyclic Adenosine Monophosphate (cAMP) Pathway
por: Kang, Wesuk, et al.
Publicado: (2020)

Regulation of colonic apical potassium (BK) channels by cAMP and somatostatin
por: Perry, M. D., et al.
Publicado: (2009)

Metabolic benefits of inhibiting cAMP-PDEs with resveratrol
por: Chung, Jay H.
Publicado: (2012)

Cardiac cAMP: production, hydrolysis, modulation and detection
por: Boularan, Cédric, et al.
Publicado: (2015)

New Era of Diacylglycerol Kinase, Phosphatidic Acid and Phosphatidic Acid-Binding Protein
por: Sakane, Fumio, et al.
Publicado: (2020)

Effect of oral administration of soy-derived phosphatidic acid on concentrations of phosphatidic acid and lyso-phosphatidic acid molecular species in human plasma
por: Purpura, Martin, et al.
Publicado: (2013)

DJ-1 as a potential biomarker for the development of biocompatible multiwalled carbon nanotubes
por: Haniu, Hisao, et al.
Publicado: (2011)

Studies on the Carrier Function of Phosphatidic Acid in Sodium Transport : I. The turnover of phosphatidic acid and phosphoinositide in the avian salt gland on stimulation of secretion
por: Hokin, Lowell E., et al.
Publicado: (1960)

Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer
por: Wang, Sen, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_83d0bec261n7gk3t8udpc4dn09