Cargando…

Electrical Stimuli Are Anti-Apoptotic in Skeletal Muscle via Extracellular ATP. Alteration of This Signal in Mdx Mice Is a Likely Cause of Dystrophy

ATP signaling has been shown to regulate gene expression in skeletal muscle and to be altered in models of muscular dystrophy. We have previously shown that in normal muscle fibers, ATP released through Pannexin1 (Panx1) channels after electrical stimulation plays a role in activating some signaling...

Descripción completa

Detalles Bibliográficos
Autores principales: Valladares, Denisse, Almarza, Gonzalo, Contreras, Ariel, Pavez, Mario, Buvinic, Sonja, Jaimovich, Enrique, Casas, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839923/
https://www.ncbi.nlm.nih.gov/pubmed/24282497
http://dx.doi.org/10.1371/journal.pone.0075340

Ejemplares similares