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Electrical Stimuli Are Anti-Apoptotic in Skeletal Muscle via Extracellular ATP. Alteration of This Signal in Mdx Mice Is a Likely Cause of Dystrophy
ATP signaling has been shown to regulate gene expression in skeletal muscle and to be altered in models of muscular dystrophy. We have previously shown that in normal muscle fibers, ATP released through Pannexin1 (Panx1) channels after electrical stimulation plays a role in activating some signaling...
Autores principales: | Valladares, Denisse, Almarza, Gonzalo, Contreras, Ariel, Pavez, Mario, Buvinic, Sonja, Jaimovich, Enrique, Casas, Mariana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839923/ https://www.ncbi.nlm.nih.gov/pubmed/24282497 http://dx.doi.org/10.1371/journal.pone.0075340 |
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