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CD4(+)NKG2D(+) T Cells Exhibit Enhanced Migratory and Encephalitogenic Properties in Neuroinflammation

Migration of encephalitogenic CD4(+) T lymphocytes across the blood-brain barrier is an essential step in the pathogenesis of multiple sclerosis (MS). We here demonstrate that expression of the co-stimulatory receptor NKG2D defines a subpopulation of CD4(+) T cells with elevated levels of markers fo...

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Detalles Bibliográficos
Autores principales: Ruck, Tobias, Bittner, Stefan, Gross, Catharina C., Breuer, Johanna, Albrecht, Stefanie, Korr, Sabrina, Göbel, Kerstin, Pankratz, Susann, Henschel, Christian M., Schwab, Nicholas, Staszewski, Ori, Prinz, Marco, Kuhlmann, Tanja, Meuth, Sven G., Wiendl, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839937/
https://www.ncbi.nlm.nih.gov/pubmed/24282598
http://dx.doi.org/10.1371/journal.pone.0081455