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Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial
OBJECTIVE: To evaluate the cost-effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared to general practitioners’ care. METHODS: A multicentre randomised trial with 175 community dwelling patients newly diagnosed with mild to moderate dementia, and thei...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839971/ https://www.ncbi.nlm.nih.gov/pubmed/24282511 http://dx.doi.org/10.1371/journal.pone.0079797 |
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author | Meeuwsen, Els Melis, René van der Aa, Geert Golüke-Willemse, Gertie de Leest, Benoit van Raak, Frank Schölzel-Dorenbos, Carla Verheijen, Desiree Verhey, Frans Visser, Marieke Wolfs, Claire Adang, Eddy Olde Rikkert, Marcel |
author_facet | Meeuwsen, Els Melis, René van der Aa, Geert Golüke-Willemse, Gertie de Leest, Benoit van Raak, Frank Schölzel-Dorenbos, Carla Verheijen, Desiree Verhey, Frans Visser, Marieke Wolfs, Claire Adang, Eddy Olde Rikkert, Marcel |
author_sort | Meeuwsen, Els |
collection | PubMed |
description | OBJECTIVE: To evaluate the cost-effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared to general practitioners’ care. METHODS: A multicentre randomised trial with 175 community dwelling patients newly diagnosed with mild to moderate dementia, and their informal caregivers, with twelve months’ follow-up. Cost-effectiveness was evaluated from a societal point of view and presented as incremental cost per quality adjusted life year. To establish cost-effectiveness, a cost-utility analysis was conducted using utilities based on the EQ-5D. Uncertainty surrounding the incremental cost-effectiveness ratio (difference in costs divided by difference in effects) was calculated by bootstrapping from the original data. RESULTS: Compared to general practitioners’ care, treatment by the memory clinics was on average €1024 (95% CI: −€7723 to €5674) cheaper, and showed a non-significant decrease of 0.025 (95% CI: −0.114 to 0.064) quality adjusted life years. The incremental cost-effectiveness point estimate from the bootstrap simulation was € 41 442 per QALY lost if one would use memory clinic care instead of general practitioner care. CONCLUSION: No evidence was found that memory clinics were more cost-effective compared to general practitioners with regard to post-diagnosis treatment and coordination of care of patients with dementia in the first year after diagnosis. TRIAL REGISTRATION: ClinicalTrials.gov NCT00554047 |
format | Online Article Text |
id | pubmed-3839971 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-38399712013-11-26 Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial Meeuwsen, Els Melis, René van der Aa, Geert Golüke-Willemse, Gertie de Leest, Benoit van Raak, Frank Schölzel-Dorenbos, Carla Verheijen, Desiree Verhey, Frans Visser, Marieke Wolfs, Claire Adang, Eddy Olde Rikkert, Marcel PLoS One Research Article OBJECTIVE: To evaluate the cost-effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared to general practitioners’ care. METHODS: A multicentre randomised trial with 175 community dwelling patients newly diagnosed with mild to moderate dementia, and their informal caregivers, with twelve months’ follow-up. Cost-effectiveness was evaluated from a societal point of view and presented as incremental cost per quality adjusted life year. To establish cost-effectiveness, a cost-utility analysis was conducted using utilities based on the EQ-5D. Uncertainty surrounding the incremental cost-effectiveness ratio (difference in costs divided by difference in effects) was calculated by bootstrapping from the original data. RESULTS: Compared to general practitioners’ care, treatment by the memory clinics was on average €1024 (95% CI: −€7723 to €5674) cheaper, and showed a non-significant decrease of 0.025 (95% CI: −0.114 to 0.064) quality adjusted life years. The incremental cost-effectiveness point estimate from the bootstrap simulation was € 41 442 per QALY lost if one would use memory clinic care instead of general practitioner care. CONCLUSION: No evidence was found that memory clinics were more cost-effective compared to general practitioners with regard to post-diagnosis treatment and coordination of care of patients with dementia in the first year after diagnosis. TRIAL REGISTRATION: ClinicalTrials.gov NCT00554047 Public Library of Science 2013-11-25 /pmc/articles/PMC3839971/ /pubmed/24282511 http://dx.doi.org/10.1371/journal.pone.0079797 Text en © 2013 Meeuwsen et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Meeuwsen, Els Melis, René van der Aa, Geert Golüke-Willemse, Gertie de Leest, Benoit van Raak, Frank Schölzel-Dorenbos, Carla Verheijen, Desiree Verhey, Frans Visser, Marieke Wolfs, Claire Adang, Eddy Olde Rikkert, Marcel Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial |
title | Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial |
title_full | Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial |
title_fullStr | Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial |
title_full_unstemmed | Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial |
title_short | Cost-Effectiveness of One Year Dementia Follow-Up Care by Memory Clinics or General Practitioners: Economic Evaluation of a Randomised Controlled Trial |
title_sort | cost-effectiveness of one year dementia follow-up care by memory clinics or general practitioners: economic evaluation of a randomised controlled trial |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839971/ https://www.ncbi.nlm.nih.gov/pubmed/24282511 http://dx.doi.org/10.1371/journal.pone.0079797 |
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