Scaffold Functions of 14-3-3 Adaptors in B Cell Immunoglobulin Class Switch DNA Recombination

Class switch DNA recombination (CSR) of the immunoglobulin heavy chain (IgH) locus crucially diversifies antibody biological effector functions. CSR involves the induction of activation-induced cytidine deaminase (AID) expression and AID targeting to switch (S) regions by 14-3-3 adaptors. 14-3-3 ada...

Descripción completa

Detalles Bibliográficos
Autores principales: Lam, Tonika, Thomas, Lisa M., White, Clayton A., Li, Guideng, Pone, Egest J., Xu, Zhenming, Casali, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840166/
https://www.ncbi.nlm.nih.gov/pubmed/24282540
http://dx.doi.org/10.1371/journal.pone.0080414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840166/
https://www.ncbi.nlm.nih.gov/pubmed/24282540
http://dx.doi.org/10.1371/journal.pone.0080414

Ejemplares similares