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Scaffold Functions of 14-3-3 Adaptors in B Cell Immunoglobulin Class Switch DNA Recombination

Class switch DNA recombination (CSR) of the immunoglobulin heavy chain (IgH) locus crucially diversifies antibody biological effector functions. CSR involves the induction of activation-induced cytidine deaminase (AID) expression and AID targeting to switch (S) regions by 14-3-3 adaptors. 14-3-3 ada...

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Detalles Bibliográficos
Autores principales:	Lam, Tonika, Thomas, Lisa M., White, Clayton A., Li, Guideng, Pone, Egest J., Xu, Zhenming, Casali, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840166/ https://www.ncbi.nlm.nih.gov/pubmed/24282540 http://dx.doi.org/10.1371/journal.pone.0080414

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